420
KLINICKÁ341804301074588109168189242288347
FARMAKOLOGIE708804301074392139212266313373416475534555599
A13288043010753
FARMACIE1402804301074292139211266317337381
/18048043010757
Klin1880804301077091109157
Farmakol2057804301074278105179220258305325
Farm2402804301074178104179
2022;36(4):123-1282601804301074386128172187231275298340361376413450494522560598640
/32618043010777
www.klinickafarmakologie.cz4568804301076513320121425327329234035839843647950254457164568672477179183988990895196610061045
1281308026012657110168
HLAVNÍ341207012670127198263336370
TÉMA732207012658115205275
Co34136501063271
je42736501062355
nového49736501064081118150191232
v744365010637
terapii7963650106306298140175192209
migrény?102036501065370109145177218255284
30.343556085367287
Camporeale4455570834073131170209231265296312347
A,8075570834155
Kudrow8775570833572111133170221
D,11135570834656
Sides1185557083324786121148
R,13485570833549
Wang14135570835788126165
S,15945570833245
Van16545570833667105
Dycke17745570834678110140174
A,19645570834055
Selzler343657083326783112127162183
KJ,541657083336173
Stauffer629657083305184121141160194215
VL.859657083336680
A95465708338
phase10086570833674106133168
3,11916570833243
long-term,1250657083125088127149172205226285297
open-label15636570833474109147169186218257292308
safety18866570832356751103437570832256
study414757083315593132164
of5947570834262
Galcanezumab671757083498297130163201236266304362395434
in11217570832058
patients1194757083447799114149188209237
with1447757083567194132
migraine.15957570836278117138171186224260272
BMC18827570834196137
Neurol3438570834580117139176192
2018;18(1):188.5508570833468100131143173204223255270281311342378391
31.343956085366981
Mulleners4399570835492107122157195230251279
WM,73395708357111125
Kim8739570833451109
BK,997957083347085
Láinez1097957083316479117152182
MJA,12949570835480120134
Lanteri-Minet14439570833164102124158179194217273288326361383
M,18429570835367
Pozo-Rosich192495708335713431057083296791129168195211244282
P,64110570834146
Wang70310570836496135175
S,89410570833851
Tockhorn-Heidenreich96110570833974107138178217240279302349385401440476515537572587620659
A,163610570834762
Aurora171310570834785107145168201
SK,19301057083397489
Nichols3431157083456193131170186213
RM,57111570834197111
Yunes-Medina69811570834076114150177198255291331346384417
L,113111570833750
Detke119711570835187109140175
HC.138711570835091105
Safety15071157083387291126149183
and170511570833876116
efficacy183611570834058769412716034312570833266
of42512570834363
galcanezumab5041257083457894127160199235266305364398438
in95812570832059
patients103312570834579101117153192214242
for12911257083246385
whom139212570835797136196
previous160412570834467102135151190229256
migraine1876125708364801203431357083215571110145
preventive50413570834567102135171210232248281316
medication836135708364100141156189223245261300340
from11921357083244785144
two135213570832882121
to148913570832765
four157013570832463102123
categories17091357083377194128169208230247282310
had34314570833870109
failed467145708322567186121160
(CONQUER):64314570832261107152200245278313332344
a1002145708336
multicentre,105314570836199114137152184218256277299333345
randomised,14131457083245795134173231246272307347359
double-178814570834280118157173208231
-blind,343155708321627995134174187
placebo-controlled,5461557083456295128163203243267302340380402424462479495531571585
phase114715570834484117145181
3b134415570834080
trial.1440155708327506699115128
Lancet158415570833872111145179202
Neurol.180215570835187126148187203217
2020;19(10):814-825.34316570833468101135148178208228259291309321356388419442478511546558
32.3431756085367186
Detke44417570835085107137172
HC,63117570834889102
Goadsby74817570834886119159185224255
PJ,10181757083395971
Wang110417570836193131170
S,128917570833749
Friedman13541757083365671106145203236274
DI,16431757083496578
Selzler17361757083367187116132167188
KJ,19391757083396779
Aurora3431857083417798135156189
SK.5471857083306479
Galcanezumab6411857083417489121153191225255292350382421
in107718570831249
chronic11421857083286687123162176208
migraine.136518570835570108129162177214249261
The164118570833069103
randomized,1759185708318518912716522323834319570832862101113
double-blind,47119570833573111149165199222262277292329368380
placebo-controlled8661957083365284115149187226249282318356378399436451466500539
REGAIN142019570833366110151166211
study.16461957083234684122154163
Neurology1824195708342771141351723432057083155393125
2018;91(24):e2211-e2221.48320570833468100131143179211226260291309321355390424456483502539573608642674683
33.3432156085367084
Vernieri4422157083336586124138172193208
F,66521570833035
Altamura7152157083385375107164201222255
C,98421570833750
Brunelli10492157083325391128163178192207
N,127121570834154
Costa13402157083377399122154
CM,150921570833791105
Aurilia16282157083387595111125140171
C,181421570833750
Egeo187921570832967101139
G,21385570834457
Fofi2210557083316986103
L,23295570833043
Favoni2388557083306091129168183
V,25865570833443
Pierangeli2644557083344883104137175214249265280
G,29395570834256
Lovati3010557083306799132154169
C,31955570833851
Aguggia32615570834078116155194209241
M,35175570835367
d‘Onofrio35995570833750981361751942138657083213674
F,22286570833642
Doretti22856570834988109143166190205
A,25066570834459
Di25806570834965
Fiore2660657083365189111145
P,28206570833943
Finocchi2879657083365189127160191229244
C,31386570834457
Rao32106570833972110
R,33356570834054
Bono34046570833977116154
F,35746570833642
Ranieri3631657083397211012516021387570832136
A,21907570834458
Albanese2264757083456099132170205232267
M,25467570835872
Cevoli26337570834478110147163178
S,28277570833649
Barbanti2891757083397293133166204225241
P;31477570833951
GARLIT32147570834789125157173207
Study3436757083365795134166
Group.36187570834769106144183196
Galcanezumab2138857083447894126160199234264303362395435
for2589857083246285
the26898570832766102
prevention28078570834466101134169208230246285324
of31478570834362
high3225857083435999137
frequency3378857083244781122160196234267301
episodic369585708340809621389570832665105120153
and23069570833776115
chronic2437957083367596134173188220
migraine26739570836378117139172187226261
in29509570832058
real3023957083266193109
life314795708320355590
in32529570832059
Italy:332695708320437692124137
a347995708337
multicenter35329570836310111613915418722125921381057083225677
prospective223110570834466103130170206239263278311346
cohort259310570833673112151173198
study28061057083325593133165
(the29871057083234583119
GARLIT312110570834991128160176210
study).33471057083315593132165183194
J3557105708329
Headache360210570834985117156189213811570833169104
Pain.22581157083356782120133
2021;22(1):35.240611570833468101133141176211228260274286321354366
34.21381256085367388
Ashina224212570834269107122160192
M,245012570835568
Saper253312570833366105141162
J,271012570832537
Cady276212570834073112144
R,292112570833650
Schaeffler298612570833365103136171189207225260281
BA,32821257083367791
Biondi33881257083365189127166182
DM,3585125708346101114
Hirman37141257083456081213813570835790128
J,228113570832234
Pederson233113570833367106141162189228266
S,261213570833144
Allan26711357083395570102140
B,282613570833447
Smith288813570833188103126164
J.306713570832335
Eptinezumab31171357083317092107145180210248306338378
in351013570831351
episodic35761357083327187113151191206238
migraine:213814570835772111132165181218253266
A2419145708345
randomized,24791457083245795134172230245275309348361
double-blind,285514570834280118157173208231271287302340379391
placebo-controlled32621457083425890122156195234257291328366388409446462477512552
study21381557083264987126158
(PROMISE-1).23121557083185489137192207239272293324338349
Cephalalgia.267715570834073113151183199231246285300332346
2020;40(3):241-254.303815570833468101135148183219238272289301336368398417448483518531
35.21381656085357084
Lipton22371657083294482104140178
RB,24291657083336981
Saper252516570832962100135156
J,269516570832233
Ashina274316570833865103117154186
M,294416570835164
Biondi30231657083334785122161175
D,321316570834353
Bhattacharya328116570833270102123147179210248279300333366
S,366216570832941
Hirman37181657083415677213817570835790128
J,228117570832436
Schaeffler233217570833264102134169188206223258279
B,262717570833447
Cady269017570833972111143
R.284817570833549
A2913175708340
phase296817570833877109136171
3,315417570833345
randomized,32151757083205391130168226241271305344357
double-358717570833876114153169204227
-blind,2138185708321607690128166179
placebo-controlled23321857083365183115148187225248281318356377398435450465499538
study28851857083244784123154
to305418570831956
evaluate31251857083316395110147179200234
the33741857083195691
efficacy3480185708331496785116149180213
and370818570832967106
safety21381957083265978113135169
of232219570833554
eptinezumab23921957083317092108146181210248306339378
for27851957083165475
the28761957083195792
preventive29841957083365792124158196218233266300
treatment32991957083194175107129187222260281
of359619570833554
chronic3665195708329678812521382057083385385
migraine:223820570836378117138171186224259272
Results252520570834176103140155178205
of274620570834262
the282320570832765100
PROMISE-2293820570834176124179195227259281312
(PRevention32652057083245995130162196234256271309348
Of362820570835373
Migraine37162057083607521382157083385993108146181
via23342157083375385
Intravenous24352157083205879101134166200238277315341
eptinezumab279221570833978101116154189219257315348387
Safety31942157083387190125147181
and339121570833775114
Efficacy-2)3520215708338567492124157189223245276294
trial.393455708322435991106119
Neurology40685570834580118139176192230270302
2018;90:E2193-E2194u.43855570833468100131143179215228261296328358391413447483514544580618631
36.3934656085367287
Kudrow40366570833269108129166217
D,42686570834253
Cady43366570833770109140
RK,4492657083326882
Allan4589657083395469101139
B,47436570833245
Pederson48036570833366105139160187225264
SM,5082657083308497
Hirman5194657083415677135167205
J,54146570832234
Mehta5463657083518612439347570832154
LR,4003757083286478
Schaeffler4096757083296199131165183201219253274
BA.4385757083337387
Long-term44877570832966104142164186220241298
safety4800757083245775109131164
and49807570832966105
tolerability5100757083195571105126159197213228242264298
of54137570833453
eptinezumab548175708331709210739348570833873102140198231270
in42198570831553
patients4288857083397294109144182203231
with4534857083526790128
chronic4677857083327091129167182214
migraine:49068570835974113134167182220255267
a518885708333
2-year,5236857083355687122154175185
open-54368570833878113151174
-label,3934957083213769109144160172
phase41219570833978110136171
3430895708334
trial.435795708322435991106119
BMC44929570833590131
Neurol.46389570834580117139176192205
2021;21(1):126.48589570833468101132141176207222254268280310340373387
37.39341056085367181
Ailani40311057083476379112150166
J,421310570833042
McAllister427110570836093137153169184211235270292
P,457910570834045
Winner464010570836380119157193215
PK,48711057083417691
Chakhava497810570834684117148188221253287
G,528110570834963
Krog536010570834164102142
Josiassen55181057083306939341157083264274102129165203
M,415311570836074
Lindsten42431157083375391131158182216255
A,451411570834661
Sperling459111570833877113135152168206246
B,485311570834054
Ettrup49231157083385984106145185
A,512411570834661
Cady520111570834579119151
R.536811570834156
Rapid544011570834074114130170
resolution39341257083215583122139177200216255294
of424412570834363
migraine432312570836379119141174190229265
symptoms460412570833265124164187225284311
after49311257083375783117139
initiating5086125708321597598114147170186224264
the536612570832766102
preventive548412570834567102393413570833267105128144177212
treatment41621357083244681114136195231270292
eptinezumab44701357083367699115154189220259317350390
during487613570834179101117156196
a5088135708334
migraine513813570836076116138171187226261
attack:54151357083355782116149180195
results39341457083215887127144168198
from41491457083285392154
the432014570833172110
randomized444714570833066106148189250267298335377
RELIEF484114570834682116133168203
trial.50621457083315472106124138
BMC5217145708346104147
Neurol.538214570835592132156195213228
2022;22(1):205.393415570833469103138151187222240273288300336371406418
38.39341656085367288
Nežádal403816570834479108142181213228
T.428216570833140
Stanovisko43381657083315285123161193209235265302
Sekce46551657083326797128162
pro48321657083385996
diagnostiku49441657083375284123161199226249264294332
a5292165708330
léčbu53381657083134881120158
bolestí55111657083377639341757083155077100115
hlavy40641757083395486118152
České423117570834175102132166
neurologické441217570833974112133170186224264279311341375
společnosti480217570832866105121156189227265292315330
ČLS514717570834173107
JEP52701757083255893
k5379175708330
personálnímu5425175708339759612316239341857083387187126141200239
a4189185708337
technickému42421857083286296135173189222253288347385
vybavení464318570833873113147179215254269
Center492818570834680119142176198
pro514218570834567105
diagnostiku52631857083445992132171210238261277308347
a3934195708332
léčbu39811957083175285124162
bolestí41581957083418096131158181196
hlavy43701957083405587119153
a4538195708334
ke458819570833266
způsobu466919570833171109135173213251
organizace493519570834062100132170185214248280314
jejich5264195708317526782114152
sítě5432195708328436599
se554619570832964
zaměřením393420570832862120154175209247262320
na426920570833769
biologickou43542057083385391107145185200232262300338
léčbu47072057083144982121159
migrény.488120570835772111132166204235245
Cesk514120570833973100130
Slov52862057083324785117
Neurol541920570834479116138175191
N3934215708345
2022;85(3):263-265.399421570833468101136148183217235269286298333367400422453487520532